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Abbexa Ltd
osteopontin (spp1) antibody  Osteopontin (Spp1) Antibody, supplied by Abbexa Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/anti+spp1+polyclonal+antibody/pmc10377083-27-2-13?v=Abbexa+Ltd Average 90 stars, based on 1 article reviews
osteopontin (spp1) antibody - by Bioz Stars,
2026-07
90/100 stars
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OriGene
osteopontin (spp1) rabbit polyclonal antibody Osteopontin (Spp1) Rabbit Polyclonal Antibody, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/anti+spp1+polyclonal+antibody/origene___r1565?v=OriGene Average 90 stars, based on 1 article reviews
osteopontin (spp1) rabbit polyclonal antibody - by Bioz Stars,
2026-07
90/100 stars
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The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found
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Rabbit anti-Mouse Spp1 Polyclonal Antibody
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Rabbit anti-Human SPP1 Polyclonal Antibody
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OSTEOPONTINin frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.http://www.creative-diagnostics.com/Anti-OSTEOPONTIN-Pab-237119-147.htm
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Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10
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Osteopontin (OPN or Early T-Lymphocyte Activation-1: Eta-1), also referred to as transformation-associated secreted phosphoprotein, bone sialoprotein I, and minopotin, is a highly phosphorylated and glycosylated phosphoprtein that is expressed in many tissues. It is acidic,
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Image Search Results
Journal: Biomolecules
Article Title: Pro-Calcifying Role of Enzymatically Modified LDL (eLDL) in Aortic Valve Sclerosis via Induction of IL-6 and IL-33
doi: 10.3390/biom13071091
Figure Lengend Snippet: The primary antibodies used for immunohistochemistry and Western blot analysis.
Article Snippet: SPP1 ,
Techniques: Immunohistochemistry, Western Blot
Journal: Biomolecules
Article Title: Pro-Calcifying Role of Enzymatically Modified LDL (eLDL) in Aortic Valve Sclerosis via Induction of IL-6 and IL-33
doi: 10.3390/biom13071091
Figure Lengend Snippet: List of TaqMan gene expression assays.
Article Snippet: SPP1 ,
Techniques: Gene Expression, Gene Assay
Journal: Biomolecules
Article Title: Pro-Calcifying Role of Enzymatically Modified LDL (eLDL) in Aortic Valve Sclerosis via Induction of IL-6 and IL-33
doi: 10.3390/biom13071091
Figure Lengend Snippet: eLDL enhances phosphate-induced calcification in cultured human VICs/myofibroblasts. ( A ) Representative example of confluent monolayers of human VICs/myofibroblasts treated with 1 mM phosphate containing pro-calcifying medium (PM) with (wells 11 & 33 containing 2.5 µg/mL eLDL, wells 12 & 34 containing 5 µg/mL eLDL) or without eLDL (wells 10 & 32) as indicated. Cells cultured in PM containing 1 mM inorganic phosphate (P i ) served as controls. Cells were fixed and calcium phosphate deposits were stained with alizarin red pH 4.4. ( B ) For quantification of the alizarin red staining, the alizarin–Ca 2+ complexes were extracted by addition of CPC. The amount of released dye was measured by spectrophotometry at 570 nm. ( C ) qPCR analysis of osteogenic gene mRNA in cultured VICs/myofibroblasts incubated for 7 days in PM containing 1 mM inorganic phosphate (P i ) in the presence (5 µg/mL) or absence of eLDL (control). The mRNA expression levels were normalized to GAPDH according to the 2 −ddCT method. Results from 12 independent experiments are shown. Bar values are means ± SD. ( D ) eLDL induced ANGPTL4 gene expression in VICs/myofibroblasts. ANGPTL4 gene expression was determined for cells exposed to eLDL (5 μg/mL) in combination with PM 1 mM P i for 7 days. Untreated cells (PM with 1 mM P i ) served as control. Results are presented as means ± SD, n = 12, *** p < 0.001, ** p < 0.01, and * p < 0.05. ( E ) Immunohistochemical analysis of osteogenic proteins in AS. Representative sections of Grade 4 aortic valve calcification for ( a ), ENPP1, and ( b ), SPP1. Note the predominant localization of the different antigens around calcified areas. In all panels, the fibrosa with the aortic side of the valve is to the top.
Article Snippet: SPP1 ,
Techniques: Cell Culture, Staining, Spectrophotometry, Incubation, Control, Expressing, Gene Expression, Immunohistochemical staining